2. Signaling Pathways
  3. GPCR/G Protein
    Neuronal Signaling
  4. Melanocortin Receptor
  5. MC4R Isoform
  6. MC4R Inhibitor

MC4R Inhibitor

MC4R Inhibitors (2):

Cat. No. Product Name Effect Purity
  • HY-110123
    ML-00253764 hydrochloride
    		Inhibitor 99.29%
    ML-00253764 hydrochloride is a brain penetrant nonpeptidic melanocortin receptor 4 (MC4R) antagonist with a Ki and IC50 of 0.16 μM and 0.103 μM, respectively. ML-00253764 can cross blood-brain barrier.
  • HY-11029
    SNT-207707
    		Inhibitor 99.54%
    SNT-207707 is a selective, potent and orally active melanocortin MC-4 receptor antagonist with an IC50 of 8 nM (binding) and 5 nM (function) on the MC-4 receptor. SNT-207707 can cross blood-brain barrier.